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Swedish researchers have created the most detailed cell atlases of the human brain available to date. In two parallel projects, the research team from Karolinska Institutet analyzed millions of cell nuclei from human brains across a range of developmental stages. Chief among the study’s wide-ranging findings was the broad diversity of neurons found in the ...

A groundbreaking study conducted by researchers from the University of Ottawa is shedding new light on Huntington’s disease. The research focused on VGLUT3, a transporter protein, and its role in modulating the development of Huntington’s disease in a mouse model. The team’s initial findings could ultimately enhance our understanding of this devastating neurological disorder in ...

Neurodegenerative disorders, such as Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease, are characterized by the accumulation of protein deposits known as amyloids in the brain. Despite extensive research into the cause and toxicity of amyloids, little has been understood regarding the initial step in amyloid formation. But in a groundbreaking new study published in eLife, ...

As of 2020, over 2.8 million people worldwide live with multiple sclerosis (MS), a debilitating chronic autoimmune disorder of the brain and spinal cord. When a person has MS, the body attacks itself — more specifically, it attacks myelin, the fatty substance that protects the nerve fibers in the brain and spinal cord. While multiple ...

Alzheimer’s disease is a devastating neurodegenerative disorder that affects millions of individuals worldwide. While research has made significant strides in understanding the underlying mechanisms of the disease, effective treatments remain elusive. However, a recent study published in Nature Medicine has uncovered a new genetic variant that appears to confer protection against Alzheimer’s disease. The study, ...