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Therapeutic Areas

Newly Identified Schizophrenia Treatment Target Offers Hope
graphic illustration, two faces facing opposite directions, more faces in background, multi-colored
Schizophrenia is a chronic and severe psychiatric disorder that requires lifelong treatment. While schizophrenia does not have a cure, the most common and successful method of treating and managing symptoms has historically been a combination of antipsychotic medications and psychotherapy. However, this treatment regimen has limitations. While antipsychotic medications are widely available and can be ...
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Researchers Use Open Field Test to Explore the Connection Between Anxiety, PTSD, and Myelin
White matter - neurons with myelinated axons, oligodendrocytes forming the myelin sheaths, fibrous astrocytes, and microglia cells
An estimated one in 11 people is diagnosed with post-traumatic stress disorder, or PTSD. People with PTSD struggle with intense anxiety that lingers long after the traumatic event, which can make day-to-day life extremely difficult. But now, a new study sheds light on brain characteristics of individuals with PTSD, paving the way for innovative treatments ...
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5xFAD Transgenic Mouse Model Facilitates AD Breakthrough
Alzheimers disease, neuron with amyloid plaques, illustration
Reactive oxygen species, or ROS, are unstable molecules produced during mitochondrial metabolism. These molecules can cause a host of problems, attacking brain tissue and causing oxidative damage. Now, a group of scientists has found a link between ROS and Alzheimer’s disease (AD), demonstrating that AD progression is closely associated with oxidative brain damage caused by ...
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Could the NPC1 Gene Help Fight COVID-19?
Named for the disease it causes when mutated (Niemann-Pick Disease Type C), the NPC1 gene is located on human chromosome 18. Its normal function is to provide instructions for making a protein located in the cell’s membrane of endosomes and lysosomes. The resulting protein, also called NPC1, regulates the movement of cholesterol and fatty cells in these ...
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