These tests are used to measure motor coordination, particularly of the hind limbs.
Animals are trained and tested to traverse an elevated narrow beam which is suspended between a start platform and the animals home cage. The time to fulfill the task and the number of foot slips are recorded. The test is videotaped and parameters are evaluated by a trained observer.
Beam Walk test of 4L/PS-NA mice. Number of total slips of 4L/PS-NA and control littermates monitored over age. n = 7 per group. Two-way ANOVA with Bonferroni’s post hoc test; Mean + SEM; ***p<0.001.