The Reeperbahn Test is a spatial learning paradigm in which male rodents have to learn the location of a female in a dry-land apparatus.
Males can freely explore the arena during learning. In the recall sessions, males are placed back in the same environment while females are absent. During the whole test, animals receive no rewards or punishments. In addition to automated behavior measurements like total locomotion activity, index of learning and recall, also the ultrasound vocalization of males and ultraviolet urine mark measurements can be performed.
Experimental set-up of the Reeperbahn test. Testing for learning and reversal learning is possible. Females are tested for estrus cycle before use.