A reduction in mitochondrial activity has been strongly linked with various neurodegenerative diseases. Moreover, several mutations have been characterized that induce age-related mitochondrial malfunction. QPS Austria provides cell culture models that address the effect of compounds on mitochondrial activity and mitochondria related cell death in vitro.
Cell lines and primary neurons can be exposed to different toxins and examined for mitochondrial activity and mitochondrial membrane depolarization.
미토콘드리아 활동(MitoTracker)
미토콘드리아 막 탈분극(JC-1)
Effect of Mitochondrial Toxins and Ca2+ Influx on Mitochondrial Function
Compound testing for the following indications: