As a leading CRO for CNS drug development, QPS Neuropharmacology is the premier provider for services with transgenic animals. We have more than 20 years of experience in generating, characterizing, and maintaining transgenic disease models and applying them for drug testing projects.
The mouse and rat models available for drug development in Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Huntington’s Disease (HD), Niemann-Pick Disease (NPC1), Gaucher Disease, Amyotrophic Lateral Sclerosis (ALS), Autism Spectrum Disorder (ASD), Schizophrenia, Frontotemporal Lobar Degeneration (FTLD), and other neurodegenerative and rare diseases allow the quantitative evaluation of compound interactions with amyloid, tau, SOD1, NPC1, TDP-43, GBA, inflammation related markers, mitochondrial deficiency and other pathologies.
The fully AAALAC-accredited Animal Facility provides all in vivo services from mouse and rat breeding, treatment, behavioral analyses, tissue sampling to delivering study reports that contain all experimental details. Animals are housed under SPF conditions in IVC systems with regular health monitoring. Our approach is based on a sequence of procedural building blocks that allow customization of any service request according to your specific needs. You have the option to select any entry point and exit point in our workflow.
Take advantage of the large assortment of rodent strains available at QPS Neuropharmacology, provide your own animals or arrange an external shipment to the QPS animal facility. Beside breeding, we also offer aging of animals, treatments, implantations, in vivo tissue collection, behavioral tests, and tissue sampling. In order to maximize the information obtained per tissue sample, we also offer in-house histological and biochemical analyses.
We provide fast in-house processing by experienced and well-trained staff, and work with highly reliable shipping companies to guarantee safe transfer of your valuable animals and samples.
The biobank can provide samples (brain tissue, CSF, organs, etc.) of our animal models for analyses in your laboratory.
Breeding & Aging
Just discuss your requirements with us, and we take care of your mice and rat breeding needs. Ship your own rodent model to us or decide for one of our life stock rodent models. Upon request we breed as many rodents as needed for your experiments. Once breeding is completed animals can be aged in house as long as demanded. Afterwards, animals can either be shipped to you or be used in-house for studies according to your study needs.Animal Treatment
Our expertise covers a wide range of treatment techniques in mice and rats that include the following routes but are not limited to them:In Vivo Sampling
Behavioral Tests
We offer a wide range of behavioral tests for various indications. Most tests are evaluated using rater-independent digital animal tracking systems. Can’t find what you are looking for? We are constantly establishing new tests and would be glad to develop tests according to your requirements.Tissue Sampling
Our tissue sampling team is highly trained to dissect a plethora of different tissues from mice and rats. Different euthanasia and perfusion methods can be performed depending on your experimental needs. Can’t find what you are looking for? We are constantly establishing new methods and would be glad to develop dissections according to your requirements.Statistics & Reporting
Animal experiments performed at our facility strictly adhere to Austrian and EU laws and regulations. All procedures are supervised by the Animal Care and Welfare Committee of QPS Austria and follow FELASA recommendations. The QPS Neuropharmacology animal facility is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC).