As a leading CRO for CNS drug development, QPS Neuropharmacology is the premier provider for services with transgenic animals. We have more than 20 years of experience in generating, characterizing, and maintaining transgenic disease models and applying them for drug testing projects.
The mouse and rat models available for drug development in Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Huntington’s Disease (HD), Niemann-Pick Disease (NPC1), Gaucher Disease, Amyotrophic Lateral Sclerosis (ALS), Autism Spectrum Disorder (ASD), Schizophrenia, Frontotemporal Lobar Degeneration (FTLD), and other neurodegenerative and rare diseases allow the quantitative evaluation of compound interactions with amyloid, tau, SOD1, NPC1, TDP-43, GBA, inflammation related markers, mitochondrial deficiency and other pathologies.
The fully AAALAC-accredited Animal Facility provides all in vivo services from mouse and rat breeding, treatment, behavioral analyses, tissue sampling to delivering study reports that contain all experimental details. Animals are housed under SPF conditions in IVC systems with regular health monitoring. Our approach is based on a sequence of procedural building blocks that allow customization of any service request according to your specific needs. You have the option to select any entry point and exit point in our workflow.
Take advantage of the large assortment of rodent strains available at QPS Neuropharmacology, provide your own animals or arrange an external shipment to the QPS animal facility. Beside breeding, we also offer aging of animals, treatments, implantations, in vivo tissue collection, behavioral tests, and tissue sampling. In order to maximize the information obtained per tissue sample, we also offer in-house histological and biochemical analyses.
We provide fast in-house processing by experienced and well-trained staff, and work with highly reliable shipping companies to guarantee safe transfer of your valuable animals and samples.
The biobank can provide samples (brain tissue, CSF, organs, etc.) of our animal models for analyses in your laboratory.
Animal experiments performed at our facility strictly adhere to Austrian and EU laws and regulations. All procedures are supervised by the Animal Care and Welfare Committee of QPS Austria and follow FELASA recommendations. The QPS Neuropharmacology animal facility is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC).