The Corner Turn Test measures sensorimotor impairments by unilateral damage of the dopaminergic system.
The apparatus consists of two walls that are connected in a pointed angle of 30° with a small opening at the tip of the angle so the animal’s curiosity encourages entrance into the corner. Once the animal enters the corner the attempts of turns towards the impaired or non-impaired body side are recorded. Performance of test is videotaped and the number of turns is manually counted.
Corner Turn Test of 6-OHDA and sham-lesioned mice. Sham: n = 16, 6-OHDA: n=30. Symbols present individual animals, vertical lines show mean ± SEM.