Enzyme and substrate measurements in the Gaucher disease mouse model 4L/PS-NA
GBA1 deficiency and mutations are related to Gaucher disease, but are also shown to be linked to neurodegenerative events, e.g. in Parkinsons disease. Scantox offers the analysis of GCase activity in various in vitro and in vivo models like 1. mouse embryonic fibroblasts (MEFs) of 4L/PS-NA mice and 2. CBE treated D-Line mice, respectively. Meet …