Scientific Posters

The Neuro4D Conference 2023, May 15-16 (Mainz, Germany)

We presented our newest research results in this poster:

CHARACTERIZATION OF THE hA53T-SUD MOUSE MODEL
Histological evaluation of colon tissue
Roland Rabl, Aina Porta-Darbra, Jone Etxaniz Diaz de Durana, Tina Loeffler, Magdalena Daurer, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

Oral Presentation:

INFLAMMATION AND AD: A GUIDE THROUGH PRECLINICAL DRUG TESTING SYSTEMS
Tina Loeffler, PhD

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

AD/PD™ 2023, Mar 18-Apr 1 (Gothenburg, Sweden & Virtual Event)

We presented our newest research results in these posters:

CHARACTERIZATION OF THE hA53Ttg α-SYNUCLEIN MOUSE MODEL OF PARKINSON’S DISEASE
Richard Scheytt, Marlene Mikusch, Tina Loeffler, Irene Schilcher, Joerg Neddens, Stefanie Flunkert, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

TAU PHOSPHORYLATION INCLUDING RESIDUE THR217 AND TAU AGGREGATION IN DIFFERENT IN VITRO MODELS
Tina Loeffler, Irene Schilcher, Stefanie Flunkert, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

BEHAVIORAL CHARACTERIZATION OF THE PS19 MOUSE MODEL OF ALZHEIMER’S DISEASE
Roland Rabl, Livia Breznik, Aaron Woblistin, Tobias Pendl, Magdalena Daurer, Stefanie Flunkert and Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

ACUTE AND CHRONIC ER-STRESS-INDUCED ANIMAL MODELS OF PARKINSON’S DISEASE
Paula Jauregi^1,2, Livia Breznik1, Roland Rabl¹, Stefanie Flunkert¹, Boris Philippe Chagnaud², Manuela Prokesch¹

¹QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA
²Institute for Biology, Karl-Franzens University of Graz, Graz, Austria

NEUROINFLAMATORY RESPONSE OF HUMAN DIFFERENTIATED MICROGLIA FROM HEALTHY AND ALZHEIMER DISEASE PATIENT
Izaskun Itxaso^1,2, Tina Loeffler¹, Irene Schilcher¹, Stefanie Flunkert¹, Boris Philippe Chagnaud², Manuela Prokesch¹

¹QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA
²Institute for Biology, Karl-Franzens University of Graz, Graz, Austria

WORLDSymposium™ 2023, Feb 22-26 (Orlando, FL, USA)

We presented our newest research results in these posters:

MOTOR DEFICITS IN HOMOZYGOUS 6^NEO MICE AS MODEL OF POMPE DISEASE
Stefan Ebner-Benke, Ewald Auer, Livia Breznik, Agnes Molnar-Kasza, Irene Schilcher, Stefanie Flunkert, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

MYOPATHIC AND NEURONAL PATHOLOGIES OF THE 6^NEO MOUSE MODEL OF POMPE DISEASE
Irene Schilcher, Joerg Neddens, Ewald Auer, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

SfN Meeting 2022, Nov 12-16 (San Diego, CA, USA)

We are presenting our newest research results in these posters:

PHENOTYPIC CHARACTERIZATION OF hA53Ttg MICE AS PARKINSON’S DISEASE MODEL
Tina Loeffler, Marlene Mikusch, Richard Scheytt, Joerg Neddens, Roland Rabl, Magdalena Daurer, Livia Breznik, Sara Peinkiher, Stefanie Flunkert, Spyridon Sideromenos, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring 12, 8074 Grambach, AUSTRIA

NEUROINFLAMMATION IN THE EAE MODEL OF MULTIPLE SCLEROSIS
Joerg Neddens, Magdalena Daurer, Livia Breznik, Roland Rabl, Tina Loeffler, Sara Peinkiher, Stefanie Flunkert, Manuela Prokesch

QPS Austria GmbH, Neuropharmacology, Parkring12, 8074 Grambach, AUSTRIA

FENS Forum 2022, Jul 9-13 (Paris, France)

We are presenting our newest research results in this poster:

Fmr1-KO MICE, A SUITABLE TOOL TO STUDY CORE AND SECONDARY SYMPTOMS OF AUTISM SPECTRUM DISORDERS

Shirin Sharghi^1,2, Stefanie Flunkert¹, Magdalena Daurer¹, Spyridon Sideromenos¹, Boris Philippe Chagnaud², Marcello Leopoldo³, Enza Lacivita³, Birgit Hutter-Paier¹, and Manuela Prokesch¹

¹Department of Neuropharmacology, QPS Austria GmbH, Grambach, Austria, ²Institute for Biology, Karl-Franzens University of Graz, Graz, Austria, ³Department of Pharmacy, Drug Sciences, University of Bari, Bari, Italy

WORLDSymposium™ 2022, Feb 7-11 (San Diego, CA & Virtual Event)

We are presenting our newest research results in these posters:

CHARACTERIZATION OF IN VIVO AND IN VITRO DRUG SCREENING MODELS FOR GAUCHER DISEASE BASED ON GBA-D409V-KI MICE
Tina Loeffler, Breznik Livia, Ewald Auer, Irene Schilcher, Birgit Hutter-Paier, Manuela Prokesch

Tina Loeffler, PhD will present the abstract during a moderated poster session on Thursday, February 10, 2022 from 3:00-5:00 PM (PST)

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

BEHAVIORAL CHARACTERIZATION OF HOMOZYGOUS 6^NEO MICE AS MODEL OF POMPE DISEASE
Livia Breznik, Spyridon Sideromenos, Agnes Molnar-Kasza, Roland Rabl, Stefanie Flunkert, Manuela Prokesch, Birgit Hutter-Paier

Livia Breznik, MSc will present the abstract during a moderated poster session on Thursday, February 10, 2022 from 3:00-5:00 PM (PST)

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

AD/PD™ 2022​, March 15-20 (Barcelona, Spain & Virtual Event)

We are presenting our newest research results in these posters:

BEHAVIORAL CHARACTERIZATION OF HOMOZYGOUS 6^NEO POMPE MICE
Spyridon Sideromenos, Agnes Molnar-Kasza, Livia Breznik, Roland Rabl, Stefanie Flunkert, Manuela Prokesch, Birgit Hutter-Paier

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

HUMAN ALZHEIMER’S DISEASE TAU SEEDS INCREASE TAU SEEDING AND UPTAKE IN DIFFERENT IN VITRO MODELS
Irene Schilcher, Tina Loeffler, Manuela Prokesch, Birgit Hutter-Paier

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

INCREASED RESPONSE OF PRIMARY ADULT MICROGLIA FROM 5xFAD MICE TO PRO-INFLAMMATORY STIMULI
Irene Schilcher, Tina Loeffler, Manuela Prokesch, Birgit Hutter-Paier

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

EDARAVONE REDUCES TDP-43 LEVEL BUT NOT STRESS GRANULE FORMATION IN SODIUM ARSENITE TREATED TDP-43 OVEREXPRESSING CELLS
Irene Schilcher, Tina Loeffler, Manuela Prokesch, Birgit Hutter-Paier

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

NEUROPROTECTIVE EFFECTS OF ASTAXANTHIN IN PRECLINICAL MODELS OF ALZHEIMER’S DISEASE
Babalola Joshua Adekunle^1,2, Löffler Tina², Schilcher Irene², Manuela Prokesch², Gerald Hoefler¹ and Birgit Hutter-Paier²

¹Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria, ²QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

Oral Presentations:

DISTRIBUTION OF TAU PHOSPHORYLATION AT SEVERAL RESIDUES AFTER INJECTION OF PATIENT-DERIVED SEEDS IN A TAU MOUSE MODEL
Irene Schilcher, Tina Löffler, Martina Scharf, Magdalena Daurer, Joerg Neddens, Manuela Prokesch, Birgit Hutter-Paier

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

BEHAVIORAL CHARACTERIZATION OF THE hA53Ttg OF PARKINSON’S DISEASE
Roland Rabl, Magdalena Daurer, Livia Breznik, Helena Aspernig, Stefanie Flunkert, Birgit Hutter-Paier, Manuela Prokesch

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

The Neuro4D Conference 2022, May 16-17 (Mainz, Germany)

We are presenting our newest research results in these posters:

INCREASED RESPONSE OF 5XFAD MOUSE PRIMARY ADULT MICROGLIA TO DIFFERENT PRO-INFLAMMATORY STIMULI
Roland Rabl, Irene Schilcher, Tina Loeffler, Birgit Hutter-Paier, Manuela Prokesch

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

INJECTION OF PATIENT-DERIVED TAU SEEDS IN THE HIPPOCAMPUS OF HTAU MICE RESULTS IN TAU PHOSPHORYLATION AT SEVERAL RESIDUES
Roland Rabl, Irene Schilcher, Tina Loeffler, Martina Scharf, Magdalena Daurer, Joerg Neddens, Birgit Hutter-Paier, Manuela Prokesch

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

A NEW HUMAN Α-SYNUCLEIN A53T MOUSE MODEL EXHIBITING MULTIPLE PD-LIKE PHENOTYPES
Manuela Prokesch

Manuela Prokesch, PhD will be giving a presentation on Monday, May 16, 2022 at 14:00 (CEST)

QPS Austria GmbH, Parkring 12, 8074 Grambach, Austria

17^th ANA Meeting 2021 (Austrian Neuroscience Association)

We are presenting our newest research results in this poster:

BEHAVIOURAL CHARACTERIZATION OF THE FMR1 KNOCK-OUT MOUSE MODEL OF AUTISM SPECTRUM DISORDER (ASD)

Shirin Sharghi^1,2, Magdalena Daurer¹, Stefanie Flunkert¹, Boris Philippe Chagnaud², Marcello Leopoldo³, Enza Lacivita³ and Birgit Hutter-Paier¹

¹Department of Neuropharmacology, QPS Austria GmbH, Grambach, Austria, ²Institute for Biology, Karl-Franzens University of Graz, Graz, Austria, ³Department of Pharmacy-Drug Sciences, University of Bari, Bari, Italy

Alzheimer’s Association International Conference®

We are presenting our newest research results in this poster:

ASTAXANTHIN ENHANCES LRP1-MODULATED INSULIN SENSITIVITY AND AMYLOID BETA CLEARANCE IN AN IN VITRO BLOOD-BRAIN BARRIER MODEL

Joshua Adekunle Babalola^1,2,3, Magdalena Lang², Meekha George², Anika Stracke², Jelena Tadic⁴, Frank Madeo⁴, Achim Lass⁴, Gerd Leitinger⁵, Birgit Hutter-Paier³, Gerald Hoefler¹ and Ute Panzenboeck²

¹Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria, ²Division of Immunology and Pathophysiology, Otto Loewi Research Center, Medical University of Graz, Austria; ³QPS Austria GmbH, Department Neuropharmacology; ⁴Institute of Molecular Biosciences, University of Graz, Graz, Austria; ⁵Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Austria.