Scientific References – Publications
QPS Neuropharmacology
QPS encourages its scientists to publish and disseminate the results of their high quality research which is mostly done in close collaboration with our clients.
The following articles are hyperlinked to the original journal article or an abstract of the article:
Quantification of Huntington’s Disease Related Markers in the R6/2 Mouse Model
Estibaliz Etxeberria-Rekalde, Saioa Alzola-Aldamizetxebarria, Stefanie Flunkert, Isabella Hable, Magdalena Daurer, Joerg Neddens and Birgit Hutter-Paier
Front. Mol. Neurosci., 11 January 2021 | https://doi.org/10.3389/fnmol.2020.617229
Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice
Johanna Michael, Diana Bessa de Sousa, Justin Conway, Erick Gonzalez-Labrada, Rodolphe Obeid, Julia Tevini, Thomas Felder, Birgit Hutter-Paier, Horst Zerbe, Nadine Paiement, Ludwig Aigner
Pharmaceutics. 2020 Dec 23;13(1):E12. doi: 10.3390/pharmaceutics13010012.
Constant Levels of Tau Phosphorylation in the Brain of htau Mice
Joerg Neddens, Magdalena Daurer, Tina Loeffler, Saioa Alzola Aldamizetxebarria, Stefanie Flunkert, Birgit Hutter-Paier
Front Mol Neurosci 2020 Aug 28;13:136. doi: 10.3389/fnmol.2020.00136. eCollection 2020.
Correlation of Pyroglutamate Amyloid β and Ptau Ser202/Thr205 Levels in Alzheimer’s Disease and Related Murine Models
Joerg Neddens, Magdalena Daurer, Stefanie Flunkert, Kerstin Beutl, Tina Loeffler, Lauren Walker, Johannes Attems, Birgit Hutter-Paier
PLoS One. 2020 Jul 9;15(7):e0235543. doi: 10.1371/journal.pone.0235543. eCollection 2020.
Validation of Behavioral Phenotypes in the BACHD Rat Model
Arianna Novati, Giuseppe Manfré, Stefanie Flunkert, Johanneke E Van der Harst, Judith R Homberg, Robert Wronski, Huu Phuc Nguyen
Behav Brain Res. 2020 Jun 20;112783. doi: 10.1016/j.bbr.2020.112783.
Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value
Tina Loeffler, Irene Schilcher, Stefanie Flunkert, and Birgit Hutter-Paier
Front. Neurosci., 11 June 2020
CD8 + T-cells Infiltrate Alzheimer’s Disease Brains and Regulate Neuronal- And Synapse-Related Gene Expression in APP-PS1 Transgenic Mice
Unger MS., Li E., Scharnagl L., Poupardin R., Altendorfer B., Mrowetz H., Hutter-Paier B., Weiger TM., Heneka MT., Attems J., Aigner L.
Brain Behav Immun 2020 May 29;S0889-1591(19)31573-9. doi: 10.1016/j.bbi.2020.05.070.
Transgene integration causes RARB downregulation in homozygous Tg4-42 mice.
Hinteregger B, Loeffler T, Flunkert S, Neddens J, Birner-Gruenberger R, Bayer TA, Madl T, Hutter-Paier B.
Sci Rep. 2020 Apr 14;10(1):6377. doi: 10.1038/s41598-020-63512-8.
The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies.
Marschallinger J., Altendorfer B., Rockenstein E., Holztrattner M., Garnweidner-Raith J. Pillichshammer N., Leister I., Hutter-Paier B., Strempfl K., Unger MS., Chishty M., Felder T., Johnson M., Attems J., Masliah E., Aigner L.
Neurotherapeutics. 2020 Feb 18. doi: 10.1007/s13311-020-00836-3.
Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer’s-like mice.
Crehan H., Liu B., Kleinschmidt M., Rahfeld JU., Le KX., Caldarone BJ., Frost JL., Hettmann T., Hutter-Paier B., O’Nuallain B., Park MA., DiCarli MF., Lues I., Schilling S., Lemere CA.
Alzheimers Res Ther. 2020 Jan 13;12(1):12. doi: 10.1186/s13195-019-0579-8.